PDZ Proteins Organize Synaptic Signaling Pathways
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چکیده
منابع مشابه
PDZ Proteins Organize Synaptic Signaling Pathways
ion channels and receptors. Like rapsyn and gephyrin, MAGUKs may directly cluster interacting receptors at synapses. However, there is evidence that MAGUKs play and Program in Neuroscience additional roles in synaptic organization by linking inter-University of California at San Francisco acting receptors to downstream signal-transducing en-San Francisco, California 94143 zymes and regulating t...
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InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision. Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.
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ژورنال
عنوان ژورنال: Cell
سال: 1998
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(00)81179-4